Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients
Identifieur interne : 001F56 ( Main/Exploration ); précédent : 001F55; suivant : 001F57Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients
Auteurs : Hazem Assi [Liban] ; Eman Sbaity [Liban] ; Mahmoud Abdelsalam [Canada] ; Ali Shamseddine [Liban]Source :
- BioMed Research International [ 2314-6133 ] ; 2015.
Abstract
Sentinel lymph node biopsy (SLNB) emerged in the 1990s as a new technique in the surgical management of the axilla for patients with early breast cancer, resulting in lower complication rates and better quality of life than axillary lymph node dissection (ALND). Today SLNB is firmly established in the armamentarium of clinicians treating breast cancer, but several questions remain. The goal of this paper is to review recent work addressing 4 questions that have been the subject of debate in the use of SLNB in the past few years: (a) What is the implication of finding micrometastases in the sentinel nodes? (b) Is ALND necessary in all patients who have a positive SLNB? (c) How accurate is SLNB after neoadjuvant therapy? (d) Can SLNB be used to stage the axilla in locally recurrent breast cancer following breast surgery with or without prior axillary surgery?
Url:
DOI: 10.1155/2015/405949
PubMed: 25821800
PubMed Central: 4363495
Affiliations:
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Box 11-0236, Riad El Solh, Beirut 1107 2020, Lebanon</nlm:aff><country xml:lang="fr">Liban</country><wicri:regionArea>Department of Internal Medicine, American University of Beirut Medical Center, Cairo Street, P.O. Box 11-0236, Riad El Solh, Beirut 1107 2020</wicri:regionArea><wicri:noRegion>Beirut 1107 2020</wicri:noRegion></affiliation></author><author><name sortKey="Sbaity, Eman" sort="Sbaity, Eman" uniqKey="Sbaity E" first="Eman" last="Sbaity">Eman Sbaity</name><affiliation wicri:level="1"><nlm:aff id="I2">Department of Surgery, American University of Beirut Medical Center, Cairo Street, P.O. Box 11-0236, Riad El Solh, Beirut 1107 2020, Lebanon</nlm:aff><country xml:lang="fr">Liban</country><wicri:regionArea>Department of Surgery, American University of Beirut Medical Center, Cairo Street, P.O. Box 11-0236, Riad El Solh, Beirut 1107 2020</wicri:regionArea><wicri:noRegion>Beirut 1107 2020</wicri:noRegion></affiliation></author><author><name sortKey="Abdelsalam, Mahmoud" sort="Abdelsalam, Mahmoud" uniqKey="Abdelsalam M" first="Mahmoud" last="Abdelsalam">Mahmoud Abdelsalam</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Medicine, Dalhousie University, 6299 South Street, Halifax, NS, Canada B3H 4R2</nlm:aff><country>Canada</country><wicri:regionArea>Department of Medicine, Dalhousie University, 6299 South Street, Halifax, NS</wicri:regionArea><wicri:noRegion>NS</wicri:noRegion></affiliation></author><author><name sortKey="Shamseddine, Ali" sort="Shamseddine, Ali" uniqKey="Shamseddine A" first="Ali" last="Shamseddine">Ali Shamseddine</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Internal Medicine, American University of Beirut Medical Center, Cairo Street, P.O. Box 11-0236, Riad El Solh, Beirut 1107 2020, Lebanon</nlm:aff><country xml:lang="fr">Liban</country><wicri:regionArea>Department of Internal Medicine, American University of Beirut Medical Center, Cairo Street, P.O. Box 11-0236, Riad El Solh, Beirut 1107 2020</wicri:regionArea><wicri:noRegion>Beirut 1107 2020</wicri:noRegion></affiliation></author></analytic><series><title level="j">BioMed Research International</title><idno type="ISSN">2314-6133</idno><idno type="eISSN">2314-6141</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Sentinel lymph node biopsy (SLNB) emerged in the 1990s as a new technique in the surgical management of the axilla for patients with early breast cancer, resulting in lower complication rates and better quality of life than axillary lymph node dissection (ALND). Today SLNB is firmly established in the armamentarium of clinicians treating breast cancer, but several questions remain. The goal of this paper is to review recent work addressing 4 questions that have been the subject of debate in the use of SLNB in the past few years: (a) What is the implication of finding micrometastases in the sentinel nodes? (b) Is ALND necessary in all patients who have a positive SLNB? (c) How accurate is SLNB after neoadjuvant therapy? (d) Can SLNB be used to stage the axilla in locally recurrent breast cancer following breast surgery with or without prior axillary surgery?</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Goker, M" uniqKey="Goker M">M. Göker</name></author><author><name sortKey="Devoogdt, N" uniqKey="Devoogdt N">N. 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Nguyen</name></author><author><name sortKey="Hansen, N" uniqKey="Hansen N">N. Hansen</name></author><author><name sortKey="Edwards, G K" uniqKey="Edwards G">G. K. Edwards</name></author><author><name sortKey="Conway, K" uniqKey="Conway K">K. Conway</name></author><author><name sortKey="Giuliano, A E" uniqKey="Giuliano A">A. E. Giuliano</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Black, D M" uniqKey="Black D">D. M. Black</name></author><author><name sortKey="Mittendorf, E A" uniqKey="Mittendorf E">E. A. Mittendorf</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Canada</li><li>Liban</li></country></list><tree><country name="Liban"><noRegion><name sortKey="Assi, Hazem" sort="Assi, Hazem" uniqKey="Assi H" first="Hazem" last="Assi">Hazem Assi</name></noRegion><name sortKey="Sbaity, Eman" sort="Sbaity, Eman" uniqKey="Sbaity E" first="Eman" last="Sbaity">Eman Sbaity</name><name sortKey="Shamseddine, Ali" sort="Shamseddine, Ali" uniqKey="Shamseddine A" first="Ali" last="Shamseddine">Ali Shamseddine</name></country><country name="Canada"><noRegion><name sortKey="Abdelsalam, Mahmoud" sort="Abdelsalam, Mahmoud" uniqKey="Abdelsalam M" first="Mahmoud" last="Abdelsalam">Mahmoud Abdelsalam</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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